Free PTCB PTCE Exam Actual Questions

The questions for PTCE were last updated On Jun 12, 2025

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Question No. 1

AMedication Guidemust be dispensed with:

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Correct Answer: B

Bupropion (Wellbutrin, Zyban) requires a Medication Guide due to risks of suicidal thoughts and neuropsychiatric effects.

Medication Guides are FDA-required leaflets given with specific medications that have serious risks.

Examples of Medications Requiring a Medication Guide:

Antidepressants (e.g., SSRIs, SNRIs, bupropion) Suicide risk

NSAIDs GI bleeding risk

Opioids Addiction risk

Fluoroquinolones Tendon rupture risk

Reference:FDA Medication Guide Requirements, ISMP Patient Safety Guidelines.


Question No. 2

Which of the followingmedications should be pulled from inventorydue to incorrect storage?

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Correct Answer: C

Comprehensive and Detailed Step-by-Step Explanation:

Shingrix (Zoster Vaccine Recombinant)must be stored in therefrigerator (2C to 8C / 36F to 46F)and shouldnever be frozen.

Explanation of Answer Choices:C. Shingrix that was stored in a freezerCorrect.Shingrixloses potencywhen frozen.A. Boostrix (Tdap) stored in a refrigerator Incorrect.Proper storage condition.B. Havrix (Hepatitis A vaccine) stored in a refrigerator Incorrect.Proper storage condition.D. Varivax (Varicella vaccine) stored in a freezer Incorrect.Varivax must be stored frozen (-50C to -15C).

Reference:

CDC Vaccine Storage & Handling Guidelines

USP <1079>: Vaccine Storage


Question No. 3

What type ofmedication erroris described asa mistake in prescribing, dispensing, or planned medication administration that is detected and corrected before reaching the patient?

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Correct Answer: D

A potential error is a mistake that is identified and corrected before it reaches the patient.

Example:A technician fillshydralazineinstead ofhydroxyzine, but the pharmacist catches the mistake before dispensing.

Reference:ISMP Medication Error Categories, PTCE Pharmacy Error Prevention Guide.


Question No. 4

A pharmacy technician should notify a pharmacist when a refill of sertraline is requested if the patient:

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Correct Answer: C

Sertraline (Zoloft)is anSSRI antidepressantused formajor depressive disorder (MDD), anxiety, and other mood disorders.Suicidal ideation(thoughts of self-harm) is aserious and potentially life-threatening side effect, especially inyoung adults. A pharmacy technicianmust notify the pharmacist immediatelyif a patient reportssuicidal thoughts, as this may require immediate medical intervention.

A . Presents new insurance coverage Incorrect; this is an administrative issue, not a clinical concern.

B . Requests the refill two days early Incorrect; a slight early refill request does not indicate a safety concern.

D . Reports improved interest and motivation Incorrect; this is apositive treatment response, not an urgent issue.

Other Answer Choices Explained:Reference:

FDA Black Box Warning for SSRIs -- Suicide Risk in Young Adults

PTCB PTCE Exam Content Outline (Medication Safety & Patient Communication)

Lexicomp Drug Monograph for Sertraline (Zoloft)


Question No. 5

When used on a prescription, "PR" indicates a particular:

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Correct Answer: A

Comprehensive and Detailed Step-by-Step Explanation:

The abbreviation 'PR' stands for 'per rectum', which is a route of administration where the medication is inserted into the rectum for absorption.

Explanation of Answer Choices:

A. Route of administration Correct. 'PR' means rectal administration (e.g., suppositories).

B. Frequency of dosing Incorrect. Frequency abbreviations include BID (twice daily), QD (once daily), etc.

C. Medication strength Incorrect. Strength is indicated by mg, mcg, etc.

D. Dosage form Incorrect. Dosage forms include tablets, capsules, solutions, etc.

Reference:

ISMP List of Common Prescription Abbreviations

PTCB Exam: Medication Order Interpretation