The Cisco 300-745 exam validates your ability to design secure network infrastructure aligned with modern security frameworks and organizational risk profiles. This exam is intended for network professionals pursuing the Cisco Certified Network Professional Security credential who need to demonstrate expertise in planning, architecting, and implementing security solutions. This page provides a structured overview of the exam syllabus, question formats, and practical preparation strategies to help you study effectively and build confidence before test day.
Use this topic map to guide your study for Cisco 300-745 (Designing Cisco Security Infrastructure) within the Cisco Certified Network Professional and Cisco Certified Network Professional Security path.
The 300-745 exam uses a mix of question types to assess both foundational knowledge and applied reasoning in security design scenarios. Questions progress in difficulty and reflect real-world decision-making contexts.
Questions are weighted toward practical application, so expect scenarios that combine multiple topics and require you to justify your design choices.
Effective preparation balances topic review, practice questions, and timed practice tests. Structure your study around the four core domains and build connections between infrastructure, applications, risk management, and automation.
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Secure Infrastructure and Risk/Events/Requirements typically account for the largest portion of the exam, as they form the foundation of security design. However, all four domains are tested, and questions often blend multiple topics, so balanced preparation across all areas is essential for success.
In practice, you start with Risk/Events/Requirements to understand business drivers and compliance mandates. You then design Secure Infrastructure to address those requirements, integrate Applications security to protect data and services, and layer in AI/Automation/DevSecOps to enable continuous monitoring and faster response. This end-to-end flow is reflected in scenario-based exam questions.
Hands-on experience with Cisco security products (firewalls, IDS/IPS, threat defense) and design tools strengthens your ability to answer scenario questions and simulation items. Prioritize labs that involve architecture design decisions, policy configuration, and interpreting security event outputs rather than memorizing command syntax.
Many candidates focus too heavily on product features and miss the design reasoning behind them. Avoid choosing answers based solely on technical correctness; instead, select options that best align with stated business requirements, risk tolerance, and compliance constraints. Also, read scenario details carefully, as subtle differences in requirements often change the correct answer.
In your final week, avoid introducing new topics; instead, review weak areas identified in practice tests and re-read explanations for questions you answered incorrectly. Do one full-length timed practice test to confirm your pacing and build confidence, then spend remaining time on targeted review of high-value concepts rather than re-studying material you already know well.
Refer to the exhibit.

A retail company recently deployed a file inspection feature using secure endpoint. The file inspection must detect and prevent the execution of malicious files on machines. During testing, logs showed that certain malicious files are still being executed despite the presence of the security measure. To understand why the threats are not being blocked, it is essential to investigate the configuration of secure endpoint policies. Which configuration is allowing the files to execute?
In the provided exhibit of the Cisco Secure Endpoint (formerly AMP for Endpoints) console, the 'Activity Details' pane on the right side provides the specific reason why the malicious file was allowed to execute. The log clearly states: 'The file was not quarantined. In audit only mode.' This indicates that while the system correctly identified the file (iodnxvg.exe) as malicious and categorized it with a threat name (W32.DFC.MalParent), it took no preventative action because of the policy configuration.
In Cisco Secure Endpoint, policies can be set to different modes. Audit Mode is typically used during the initial deployment or testing phase to gain visibility into what would be blocked without actually disrupting business operations. In this mode, the connector logs events and alerts administrators but does not move the file to a secure quarantine area. To fulfill the requirement of preventing the execution of malicious files, the security designer must change the policy from 'Audit' to a protective mode, such as Protect or Quarantine. This ensures that the engine actively intervenes when a threat signature or suspicious behavior is detected.
While the file is confirmed as malicious (negating Option A) and the system is clearly active and logging (negating Option C), the lack of enforcement is a direct result of the specific operational mode selected. Option B is incorrect because, although network blocking is a feature, the primary failure here is at the file execution/quarantine layer. This scenario emphasizes the importance of moving from a visibility-centric posture to an enforcement-centric posture in a mature secure infrastructure design.
An employee of a pharmaceutical company accidentally checked in code that contains AWS secret keys to a public GitHub repository, which exposes production resources to attackers. Which mitigation strategy must a security engineer recommend to prevent future reoccurrence?
Accidental exposure of sensitive credentials, such as API keys or AWS secrets, is a major risk in modern DevOps environments. To prevent such incidents from occurring, the most effective technical control is the implementation of a Source Code Management (SCM) precommit hook. A precommit hook is a script that runs locally on a developer's machine before a commit is finalized and pushed to a remote repository.
According to Cisco's DevSecOps design principles, precommit hooks can be configured to scan the code for specific patterns that resemble secrets (e.g., regex for AWS Access Key IDs). If the scanner detects a secret, it automatically aborts the commit, forcing the developer to remove or properly encrypt the sensitive data before the code can leave their local machine. This provides an immediate 'shift-left' safety net that stops the leak at the source.
While a Web Application Firewall (WAF) (Option A) protects against external attacks and Port Security (Option B) manages Layer 2 access, neither can prevent a developer from pushing code to GitHub. A phishing education campaign (Option C) is beneficial for general security awareness but does not provide the automated, technical enforcement required to block credential leakage. By configuring precommit hooks, the pharmaceutical company establishes a proactive defense mechanism that significantly reduces the risk of credential exposure and aligns with the automation objectives of the Cisco SDSI curriculum.
A furniture company recently discovered that the endpoint detection and response configuration flagged several malicious files on company-managed laptops. The company must enhance security to prevent known malicious files from being delivered to the network and endpoints. The new solution must enhance the company's ability to inspect and filter incoming traffic effectively. Which security product must be used to accomplish this goal?
While Endpoint Detection and Response (EDR) is excellent at catching threats that have already reached a device, the objective here is to prevent those files from being delivered in the first place by enhancing the inspection of incoming traffic. A Next-Generation Firewall (NGFW) is the correct architectural choice for this requirement because it operates at the network perimeter (or between segments) and provides deep packet inspection (DPI) far beyond the capabilities of a traditional firewall.
A Cisco Secure Firewall (NGFW) integrates multiple security services into a single platform, including Intrusion Prevention Systems (IPS), Application Visibility and Control (AVC), and Advanced Malware Protection (AMP). When malicious files are sent toward the network, the NGFW can identify them by their signature or behavior and block the transfer before the file ever reaches the internal infrastructure or endpoints. This effectively 'cleans' the traffic stream at the gate.
A traditional firewall (Option B) lacks the application-layer visibility needed to identify malicious file content, as it primarily filters based on IP and port. A host-based firewall (Option C) filters traffic at the individual device level, which is a late-stage defense rather than a network delivery prevention tool. eBPF (Option D) is a high-performance kernel technology used for observability and distributed filtering but is not a standalone 'security product' used for perimeter traffic inspection in this context. Implementing an NGFW aligns with the Cisco SAFE principle of providing a layered defense that blocks threats as far from the critical assets as possible.
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A software development company uses multiple cloud providers to host applications. The company is designing a scalable firewall solution that must meet the requirements:
Consistent security policies across multiple cloud environments.
Centralized visibility and management.
Scalability to accommodate different cloud platforms.
Which type of firewall meets the requirements?
In a multi-cloud architecture, traditional perimeter-based firewalls often create 'chokepoints' and fail to provide the granularity needed for east-west traffic between microservices across different providers. A distributed firewall is the architectural solution designed to meet these modern requirements. Unlike a centralized appliance, a distributed firewall is implemented as a software-defined layer that resides close to the workloads---often within the hypervisor or as part of a service mesh.
According to Cisco Security Infrastructure objectives, a distributed firewall allows for centralized management of a unified policy that is pushed out to all enforcement points, regardless of whether the workload is in AWS, Azure, or an on-premises data center. This ensures consistent security policies across the entire footprint. Because the enforcement is decentralized, the solution scales automatically as new cloud platforms or workloads are added. While a Traditional Firewall (Option A) lacks the multi-cloud agility, a Zone-based Firewall (Option B) is typically tied to specific physical or logical interfaces on a router, and a Host-based Firewall (Option D) is managed at the individual OS level, which becomes difficult to coordinate centrally at scale. The distributed firewall model aligns with the Cisco SAFE architectural goal of pervasive security and simplified operations in highly dynamic, heterogeneous cloud environments.
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A telecommunications company recently introduced a hybrid working model. Based on the new policy, employees can work remotely for 2 days per week if corporate equipment is used. The IT department is preparing corporate laptops to support users during the remote working days. Which solution must the IT department implement that provides secure connectivity to corporate resources and protects sensitive corporate data even if a laptop is stolen?
The Cisco Secure Client (formerly AnyConnect) is the comprehensive solution designed to handle the complexities of a hybrid workforce. To meet the company's requirements, Secure Client provides a secure VPN tunnel (SSL or IPsec) that ensures all traffic between the remote laptop and corporate resources is encrypted and authenticated.
Critically, for the scenario where a laptop is stolen, Secure Client integrates with various endpoint security modules. While it primarily handles secure connectivity, it is the platform that hosts features like Always-On VPN and management of disk encryption status. According to Cisco Security Infrastructure design principles, Secure Client acts as the unified agent on the endpoint that maintains the security posture and connectivity regardless of the user's location.
While Cisco Duo (Option B) provides essential Multi-Factor Authentication (MFA) to verify the user's identity, it does not provide the encrypted tunnel for data transit. ISE Posture (Option C) is a feature (often delivered via Secure Client) that checks the health of the device but doesn't provide the connectivity itself. Umbrella (Option D) protects the user from malicious sites and provides a roaming client for DNS/web security, but it does not replace the requirement for a secure tunnel to private corporate resources. Therefore, Secure Client is the holistic solution that bridges the gap between the remote user and the corporate data center while ensuring that the device remains under the organization's security umbrella.